Adaptogenic herbs help balance hormones by reducing cortisol, supporting progesterone and thyroid health, and enhancing estrogen metabolism. Herbs like maca, ashwagandha, Rhodiola, and chasteberry support mood, energy, and cycles without synthetic hormones.
Unlike synthetic hormone therapies, adaptogens work with your body to regulate stress, energy, and reproductive balance. This guide covers the top adaptogenic herbs, who they help, and how to use them safely, especially for women navigating PMS, perimenopause, or chronic fatigue.
What You’ll Learn Next:
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Which hormones do adaptogens influence
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The best herbs for mood, cycles, energy, and stress resilience
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How to use adaptogens based on your symptoms or lab results
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Why our MACA ULTRA™ formula outperforms generic blends
Our daily adaptogen blend is formulated to support clean energy, mood stability, and hormonal resilience. Backed by research and built without fillers, it’s the foundation for sustainable balance.
Are you curious how it works and which herb is right for your body?
Keep reading, we’ll break it all down with insights, safe usage tips, and a smarter way to support your hormones, naturally.
What Are Adaptogenic Herbs?
Adaptogens are a category of herbs and natural substances that help the body adapt to physical, emotional, and environmental stress. What makes them unique is how they work with, not against, your system. Rather than forcing hormone levels up or down, adaptogens gently support the endocrine and HPA axis (hypothalamus-pituitary-adrenal) to help bring your body back into balance.
Think of them like a thermostat for your stress and hormone response. If cortisol is too high, certain adaptogens help lower it. If energy is tanking, others nudge it upward, without overstimulation or harsh side effects. That’s why we use them in formulations like MACA ULTRA™, where hormonal stability and energy go hand in hand.
Adaptogenic herbs have deep roots in traditional medicine, literally. You’ll find them in Ayurveda (India), Traditional Chinese Medicine, and even ancient South American systems. Herbs like ashwagandha, schisandra, Rhodiola, and maca have been used for centuries to support mood, stamina, fertility, and hormonal harmony, long before adaptogen became a buzzword.
That said, here’s something I want to address head-on:
I’m afraid to take the wrong thing without knowing my hormone levels.
That’s a concern, and it’s valid. Adaptogens aren’t hormone replacements. They don’t contain estrogen or progesterone. Instead, they modulate, help your body better manage stress, and restore what’s out of sync. But if you’re dealing with ongoing fatigue, mood swings, irregular cycles, or menopause symptoms, getting baseline labs (especially for cortisol, thyroid, estrogen, and progesterone) can help guide your approach.
In short, adaptogens aren’t about hacking your hormones. They’re about restoring resilience, helping your body do what it’s built to do a little better.
Hormones Most Affected by Adaptogens
If you're looking into adaptogens for hormonal support, it's worth knowing which hormones they influence and why that matters. While adaptogens don't directly increase or decrease hormone levels like pharmaceuticals do, they can shift how your body regulates key hormones that control everything from mood to metabolism.
Here are the big four we see most affected:
Estrogen
Estrogen plays a huge role in a woman’s reproductive system, but it also influences skin, brain, and even cardiovascular health. When it’s out of balance, you’ll often feel it as PMS, heavy or irregular periods, low libido, or hot flashes during perimenopause. Some adaptogens, like maca or Schisandra, help your body regulate how it metabolizes estrogen, which is especially helpful in cases of estrogen dominance or sluggish liver detox.
Progesterone
This is the calming, stabilizing hormone. It’s key for regulating your menstrual cycle, supporting sleep, and even balancing your mood. Many women are unknowingly low in progesterone, especially in their 30s and 40s, which shows up as anxiety, short cycles, or trouble sleeping. Adaptogens like chasteberry (Vitex) and ashwagandha may support the systems that help produce or preserve healthy progesterone levels.
Cortisol
Here’s the big one, the stress hormone. When cortisol stays elevated due to chronic stress (and let’s be honest, most of us are there), it drags your entire hormonal system down with it. It competes with progesterone, disrupts estrogen balance, and even throws off your thyroid. Adaptogens like rhodiola, holy basil, and ashwagandha are incredibly effective at helping the body recalibrate and bring cortisol back to center.
Thyroid Hormones (T3, T4, TSH)
The thyroid is often the silent saboteur. It regulates metabolism, energy, and mood, but even slight imbalances can cause fatigue, brain fog, or weight gain. Ashwagandha, in particular, shows promise in supporting thyroid function indirectly through stress regulation and inflammation reduction.
What Should You Get Tested Before Starting Adaptogens?
This is one of the most common questions I get, and I wish more people asked it.
What hormone should men or women get tested for before trying herbs?
If you’re struggling with symptoms like irregular cycles, fatigue, or mood swings, I always recommend checking:
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Cortisol (saliva or blood)
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Progesterone (especially Days 19–21 of your cycle)
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Thyroid panel (TSH, Free T3, Free T4)
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Estrogen (especially estradiol)
These baseline labs give you clarity and help you pair the right adaptogens for your specific hormonal terrain. Even if you're going the natural route, data matters.
Top Adaptogenic Herbs for Hormone Balance in Women
Adaptogens aren’t a magic bullet, but the right ones, in the right combinations, can make a huge difference in how your body handles stress, cycles, and energy. Below are the adaptogenic herbs I most often recommend and why they’re especially effective for women navigating hormonal ups and downs.
Maca Root
If there’s one herb that deserves more credit in the hormone conversation, it’s maca. Traditionally used in Peru for energy, fertility, and vitality, maca is now backed by research showing its ability to support estrogen balance, libido, and perimenopause symptoms like hot flashes and fatigue.
What I like about maca (and why it’s the cornerstone of our Advanced Strength Supports Energy And Peak Performance is that it works by supporting the glands that produce them, not containing hormones. Great for women dealing with low mood, low drive, and low energy, especially during the perimenopausal transition.
Most people don’t realize maca supports men’s hormone health, too. We’ve had great feedback from men using it for stamina, focus, and healthy testosterone support.
Ashwagandha
This one gets a lot of hype, for good reason. Ashwagandha is one of the best-known adaptogens for calming cortisol, reducing anxiety, and improving sleep. It also supports thyroid function, which often takes a hit during chronic stress.
It’s especially helpful for stress-induced cycle irregularity, burnout, or adrenal fatigue. That said, it’s not one-size-fits-all.
Can it overstimulate me?
Yes, some people feel sedated, others feel weird. It often depends on dosage and timing. I suggest starting low and taking it at night to gauge your body’s response.
Rhodiola Rosea
Rhodiola is an energizing adaptogen that shines in situations of physical or mental stress. It’s excellent for mood, mental stamina, and even exercise recovery.
It indirectly supports hormone balance by lowering cortisol, which can allow estrogen and progesterone to function more freely. I often recommend this one for women who are high-achieving but running on fumes.
Rhodiola can be stimulating, so it's best taken earlier in the day, especially if you’re sensitive to energy shifts.
Chasteberry (Vitex)
Vitex is technically not an adaptogen, but it acts like one when it comes to progesterone support. It’s a go-to for women dealing with PMS, irregular cycles, or luteal phase issues (the second half of the menstrual cycle).
It works by influencing the pituitary gland, which regulates progesterone production, though it needs to be used with intention.
Don’t take it daily all month long. Vitex is best used during the luteal phase (roughly days 15–28 of your cycle). It can make things worse if misused.
Holy Basil (Tulsi)
Holy basil is a gentle yet powerful herb that supports both the nervous system and estrogen metabolism. It helps regulate cortisol and calm the mind, making it useful during both the stress-response phase and for hormonal processing through the liver.
I often recommend stacking tulsi with nutrients like magnesium glycinate or a B-complex, especially for women experiencing tension, irregular cycles, or insomnia tied to hormone shifts.
Schisandra Berry
If you haven’t heard of this one, you’re not alone. Schisandra is one of those under-the-radar adaptogens that quietly does a lot, especially for the liver, which is critical for hormone balance.
Schisandra supports estrogen detoxification, making it ideal for women with symptoms of estrogen dominance (like bloating, breast tenderness, or irregular cycles).
Everything I tried made me feel worse.
I hear this a lot. And in many cases, the problem is the detox pathways, not the hormones. That’s where Schisandra shines. It’s often the missing link before other adaptogens can do their job properly.
How to Use Adaptogens Safely & Effectively
If there’s one mistake I see people make with adaptogens, it’s this: they treat them like over-the-counter quick fixes. The truth is, these herbs are powerful, and like anything powerful, they need to be used with care, intention, and a little patience.
Dosage & Timing Tips
Start slow, always. I recommend beginning with half the suggested dose for the first few days to see how your body responds. Everyone reacts differently, especially when hormones are involved.
Most adaptogens are best taken with meals, ideally breakfast or lunch. For energizing herbs like rhodiola, you want them earlier in the day. Calming ones like Ashwagandha might be better at night.
Some adaptogens, like maca or chasteberry, work better when used cyclically instead of daily. For example:
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Maca can be taken daily but may be paused during menstruation for some women.
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Chasteberry is best during the luteal phase (roughly days 15–28 of your cycle).
Tracking your cycle and syncing your adaptogen use can improve results and reduce side effects. If your cycle is irregular, that’s even more reason to start slowly and observe.
Bloodwork First?
A lot of women ask me:
Do I need to test before using herbs?
My take: You don’t always need lab work to get started, especially if you’re dealing with general fatigue or stress. But if you’re dealing with:
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Irregular or missing periods
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Severe PMS
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Ongoing fatigue or insomnia
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Suspected thyroid issues
...then yes, testing can be incredibly helpful.
The big four labs I suggest starting with:
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Cortisol (morning saliva or blood)
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Progesterone (Days 19–21 of your cycle)
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Estrogen (Estradiol)
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Thyroid panel (TSH, Free T3, Free T4)
Knowing what’s going on under the hood helps you choose the right herb and prevents the trial-and-error spiral that so many people get stuck in.
Stacking Adaptogens with Nutrients
Adaptogens can do a lot, but they can’t do everything alone. In my experience, the people who get the best results are not taking herbs. They’re pairing them with foundational nutrients that fill in the gaps and support the systems those adaptogens are working on.
Think of it like this: adaptogens are the operators, helping manage stress and balance hormones, but nutrients are the builders that repair and fuel the system behind the scenes.
Here’s why certain nutrients matter when you’re using adaptogens:
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Magnesium (especially glycinate): Supports sleep, nervous system regulation, and estrogen detox. If cortisol is high, magnesium is probably low.
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B-vitamins (B6, B12, B5): Vital for adrenal function, neurotransmitters, and progesterone metabolism.
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Iodine: Supports thyroid hormone production, especially if you’re dealing with cold hands, fatigue, or hair loss.
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Sleep: Not a nutrient, but non-negotiable. Most hormonal issues can’t fully resolve if you’re running for 5 hours a night.
Example Stacks That Work
Here are a couple of stacks I’ve seen work well in life, and that we build around at Daily Defense®:
For Mood Swings + Low Energy
Maca + Ashwagandha + Magnesium Glycinate
Great for women feeling depleted, moody, and off-kilter during the second half of their cycle.
For Brain Fog + Hormonal Sluggishness
Rhodiola + Schisandra + B-100 Complex
A favorite for women with high stress, sluggish estrogen detox, or early burnout signs.
These stacks don’t need to be complicated or expensive. What matters is consistency and tuning in to how your body responds. Some of the best feedback we’ve had on MACA ULTRA™ comes from people who started stacking it with magnesium and sleep hygiene, not more pills.
A lot of users say they didn’t notice much until they fixed their nutrient routine. Once they did? Game-changer.
Are Adaptogens Safe During Pregnancy or Breastfeeding?
If you’re pregnant or breastfeeding, this is where we slow things down and think it through. The reality is, that most adaptogens haven’t been thoroughly studied for use during pregnancy, which means even the natural ones need to be approached with serious caution.
Are these safe while breastfeeding?
That’s a question I see a lot: not always. Just because a herb is natural does not mean it’s safe during such a delicate hormonal window. Adaptogens like rhodiola and ashwagandha can influence hormone and stress pathways, and while that’s helpful in many cases, it can be too much during lactation or gestation.
That said, some adaptogens are considered gentler than others. For example:
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Maca is often seen as the more tolerable option postpartum, though even then, it's best to get a practitioner’s okay.
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Rhodiola, schisandra, and chasteberry are generally not recommended while nursing or pregnant due to their hormonal effects and limited safety data.
Our approach is always the same: support, not guesswork. If you’re in this chapter of life, I strongly recommend working with a functional or integrative practitioner before starting anything, even something as seemingly safe as a root powder.
Your body is already doing a remarkable thing. Sometimes, less is more.
What People Wish They Knew Sooner
After talking to thousands of women over the years, and reading as many product reviews and threads, there’s a pattern that always stands out: most people didn’t know how much better they could feel until they stopped throwing random supplements at the problem and started using targeted, high-quality support.
You Don’t Need to Feel Worse Before You Feel Better
If you’ve tried adaptogens or hormone support in the past and felt off, bloated, wired, or more emotional, that’s not detox. That’s a sign your body wasn’t ready, or that the formula wasn’t right for you. A well-crafted adaptogen routine should feel stabilizing, not like a rollercoaster.
Not All Herbal Blends Are Created Equal
One of my biggest frustrations with the supplement space? The number of brands cutting corners is increasing. You’ve got to look for clean labels, no proprietary blends, and brands that are manufactured in GMP-certified, FDA-registered facilities, like we do. Our magnesium or cleanse formulas keep things transparent, potent, and safe.
Some Hormone Issues Need Specific Targeting
Adaptogens are powerful, but they’re not miracle workers. Conditions like PCOS, cystic breasts, or severe menstrual pain often require other than a generic hormone-balancing blend. You may need to combine adaptogens with blood sugar support, liver detox, or even thyroid care to move the needle.
Hormone Balance Takes Time
This one’s tough, especially when you're not feeling like yourself. But true hormonal balance can’t happen overnight. With the right support and a bit of patience, most people start noticing improvements in 3 to 6 weeks, sometimes sooner. The key is consistency, not chasing the next trending herb.
If someone had told me all this when I started building Daily Defense®, I would’ve saved years of frustration, and I hope it saves you time, too.
Daily Defense® Solutions for Hormonal Balance
Everything we create is built around one question: What does your body need to thrive today, and how can we deliver that cleanly, naturally, and effectively? When it comes to hormones, that often means starting small, stacking smart, and using ingredients your body recognizes.
Here are a few formulas I stand behind, because I’ve seen how they help people feel like themselves again:
MACA ULTRA™
This one’s our go-to adaptogenic formula for energy, libido, mood, and hormone stability. Whether you’re dealing with perimenopausal symptoms or dragging through your day, MACA ULTRA™ is crafted to support the endocrine system gently and effectively, for both women and men. It’s one of the most consistent success stories we hear from customers.
Magnesium Glycinate
If your hormones are out of balance, chances are your nervous system is too. Magnesium glycinate helps calm the adrenals, ease anxiety, and support progesterone and estrogen metabolism, making it the perfect companion nutrient for any adaptogen stack.
Youthful Cleanse
Before you balance hormones, it’s smart to clear out what’s clogging up the system. This 14-day cleanse helps the body remove waste, excess estrogen, and inflammatory toxins, all of which can mess with hormone regulation. Many customers use this as a foundational reset before beginning adaptogens.
Quality You Can Trust: Every Daily Defense® product is:
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Made in the USA
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Produced in FDA-registered, GMP-compliant facilities
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Non-GMO, clean-labeled and formulated with science-backed ingredients
I’m not interested in gimmicks. I’m interested in helping people feel like themselves again, and we built Daily Defense® to do exactly that.
Hormone Balance Is About Resilience, Not Perfection
If there’s one thing I hope you take away from this guide, it’s this: you don’t need to chase perfection to feel like yourself again. Hormones are dynamic; they shift with your cycle, your stress, your sleep, your season of life. And that’s normal.
Adaptogens aren’t a fix-all. They’re tools, powerful, natural tools that can help your body recover its rhythm, restore resilience, and adapt to whatever life throws at you. But they work best when paired with the basics: smart nutrition, solid sleep, stress management, and testing when possible.
Start small. Track how you feel. Adjust as needed. No pressure to get it perfect, make progress.
And if you’re looking for clean, effective support, know this: everything we create from MACA ULTRA™ to Magnesium Glycinate and Youthful Cleanse is designed to help you build a hormone-support routine that works.
Because when your hormones are in harmony, everything feels a little more possible.